There is growing evidence that social isolation is a significant contributor to chronic aggressive behavior and can exacerbate aggression brought on by traumatic stress. However, the neural mechanisms that link social isolation and traumatic stress to chronic aggression are poorly understood. In this project, we study how social isolation and acute traumatic stress during adolescence induce plasticity changes to limbic circuits, leading to maladaptive chronic aggression in the adult.
Publications
Nooshin Mojahed, Magdalene Pine Adjei, Elana Qasem, Sophia Aaflaq, Jessica T. Jacobs, Temitope Adu, Ben Richardson, Jacob C. Nordman,
Frontiers in Neuroscience, vol. 18, 2024
Opposing effects of NMDA receptor antagonists on early life stress-induced aggression in mice
J. C. Nordman, C. J. Bartsch, Z. Li
Aggressive behavior, vol. 48(3), 2022, pp. 365-373
J. C. Nordman
The International Journal of Biochemistry & Cell Biology, 2021
Potentiation of Divergent Medial Amygdala Pathways Drives Experience-Dependent Aggression Escalation
J. C. Nordman, X. Ma, Q. Gu, M. Potegal, H. Li, A.V. Kravitz, Z. Li
Journal of neuroscience, vol. 40(25), 2020, pp. 4858-4880
J. C. Nordman, X. Ma, Z. Li
eNeuro, vol. 7(4), 2020
